View Single Post
Old 01-31-2008, 01:16 PM   #128 (permalink)
remek
Co-Administrator
 
remek's Avatar
 
Join Date: Jan 2006
Posts: 2,907
Rep Power: 10 remek is on a distinguished road
Default

Quote:
Originally Posted by Iguana View Post
Interesting article in Circulation research about Smooth Muscle growth.

Changes in blood pressure or flow induce arterial remodeling that normalizes mechanical loads that are imposed on arterial tissue. Arteries are also under substantial longitudinal stretch (axial strain) that may be altered by growth or atrophy of tissues to which they are attached. We therefore tested whether axial strain is also regulated in a negative feedback manner through arterial remodeling. Axial strain in rabbit carotid arteries was increased from 62±2% to 97±2% without altering other mechanical loads on wall tissues. Strain was reduced within 3 days and completely normalized by 7 days. Remodeling involved tissue elaboration, endothelial cell replication rates were increased by >50-fold and smooth muscle cell replication rates were increased by >15-fold, and substantially elevated DNA, elastin, and collagen contents were recorded.

Wall Tissue Remodeling Regulates Longitudinal Tension in Arteries -- Jackson et al. 90 (8): 918 -- Circulation Research
I quickly glanced over this, so tell me if I missed something. . . But from what I gather, an increase in blood flow actually increased cell devision of smooth muscle cells.

I imagine that this has many applications to PE. Here's one:
  1. What does the Kegel do?!?! It increased blood flow/blood pressure to the penis. What does increased blood pressure do (or according to this study)? It increases smooth muscle cells. What does increased smooth muscle cells do? It increases 1) Hardness 2) Size (if the smooth muscle is the limiting factor). This could possible explain why Kegels increases both of these and why more men should Kegel - especially if they want hardness or if their smooth muscle is their limiting factor.
remek is online now   Reply With Quote