Andractim

[phallic1]

I posted this link under the "chemical" thread as well, thought a few members would find it worth a read.

Free Chemical Penis Enlargement Report

Mods, feel free to remove the link if it's outside of the forum guidelines.

[Protege]

I was going to buy this andractim stuff and try it out, but I think this is a scam but then also seeing all the TransGuy's talk about how dht made their dicks bigger is tempting me to buy the stuff. if you youtube dht you'll find the video of transmen saying how dht added 3/4" to their dicks after like 5 weeks. I just about peed myself laughing when i read a transman comment that you can "actually acheive a thumbsize penis".


I also found a problem with the thought of applying a steroid substance to my pecker really freaked me out but there is a lot of science behind what you guys are saying and decided to check into it. i found some information on the stuff and decided to share it with you all.

This is from pages 163-165 of the underground steroid user's hand book
ANABOLICS 9th ed. by William Llewellyn (you can find it on amazon)

the ebook version i found had pages that were cut off in area's so there are a few words at the edge of paragraphs that are missing.
one piece of info i'm really wish wasn't cut off was how long before it takes before your body returns to hormonal balance. the number was cut off but it was followed by the word "months" which doesn't exactly inspire me to buy the stuff, but the part about women needing to stay away from it due to clitoral enlargement kinda changed my mind a bit. anyways here you go....enjoy

Andractim® (dihydrotestosterone)

Androgenic 30-260
Anabolic 60-220
Standard Testosterone, T. propionate
Chemical Names 5-alpha-androstan-3-one-17beta-ol
5-aIpha-androstanolone
Estrogenic Activity none
Progestational Activity none

Andractim is a prescription steroid preparation that
contains the potent androgenic steroid
dihydrotestosterone. This product comes in the form of a
transdermal gel, typically containing 2.5%
dihydrotestosterone by weight in an 80gram tube. As with
Androgel, roughly 10% of the active steroid will make it
into circulation with each application.This would equate to
80 doses of 25 mg, with each dose delivering
approximately 2.5 mg of steroid to the body.
Dihydrotestosterone itself is the most active androgen in
the human body, displaying an ability to bind and activate
the androgen receptor at least three or four times greater
than that of its parent steroid testosterone. This trait,
however, is not accompanied by equally powerful anabolic
tendencies. In the case of dlhydrotestosterone, we have a
steroid that is almost purely androgenic, with only minimal
muscle-building (anabolic) action.

dihydrotestosterone is a weak muscle builder because it is
extremely open to alteration by the 3-alpha*
hydroxysteroid-dehydrogenase enzyme, responsible for
breaking down active steroids like DHT into their inactive
metabolites. 3a-HSD is present in high quantities in muscle
tissue, running interference between the outer cell
membrane and the androgen receptors that all steroid
hormones are trying to reach. In humans, little DHT ends up
actually reaching this receptor. Testosterone is very
resistant to this enzyme, however, which allows it to be a
much more effective muscle-building agent. 3a-HSD
steroid deactivation in muscle tissue causes the same
problem with Proviron (l-methyl-dihydrotestosterone).
DHT and Proviron both have very effective uses in areas
such as fat loss, hardening, increasing CNS activity, and
Pure strength gains, but they do not perform well as
anabolic agents.

History:
ihydrotestosterone was first synthesized in 1935. This
------------------------------------------------------------
strong androgen was put into consistent medical use
during the late 1950's, after a series of experiments
demonstrating that it had measurable anabolic effects.
Prior to this it was largely believed that DHT was exclusively
an androgenic substance, and was of little value clinically.
Dihydrotestosterone gels were developed more recently,
and have been investigated for a number of medical
purposes. At present, these preparations are primarily
indicated for the treatment of androgen deficiency,
gynecomastia, and insufficient genital growth.Transdermal
DHT has been successful as an androgen replacement
medication in older men at risk for developing prostate
hypertrophy largely because of its non-aromatizable
nature,409 410 as this disorder is fueled partly by estrogens.
The latter two indications are considered local applications
of the drug, and the DHT gel is applied directly to the
tissues requiring treatment.

The primary manufacturer of dihydrotestosterone gel
globally is Besins International, based in France. Besins
produces the drug under the Andractim name, selling it in
France and scarcely in other parts of Europe.
Dihydrotestosterone gels are found much less commonly
outside of Europe, and presently no such preparation is
commercially available in the United States. In 1995, U.S.
manufacturer Unimed Pharmaceuticals purchased the
rights to Andractim from Besins in the U.S., Mexico, and
Canada. The firm announced an interest in the drug for
several uses, including androgen replacement in men over
age sixty, treating benign prostate hypertrophy, and
combating HIV- associated wasting. Its use as an anabolic
may be desirable with HIV because it had been determined
that many patients lack an ability to properly convert
testosterone to DHT, and therefore lack sufficient levels of
this important androgen. It appears that Unimed has since
sold its interests in the anabolic steroid market, however,
leaving the potential reemergence of dihydrotestosterone
in the U.S. in question.


How Supplied:
Hydroalcoholic transdermal dihydrotestosterone gels are
available in select human drug markets. Composition and
dosage may vary by country and manufacturer, but
usually contain 2.5% dihydrotestosterone by weight.

Structural Characteristics:
Andractim® is a hydroalcoholic gel containing 2.5% of
dihydrotestosterone (free) by weight. It is designed to
provide a continuous transdermal delivery of
dihydrotestosterone for 24 hours following application to
the skin. Approximately 10% of the applied dose is
absorbed across the skin during each 24-hour period.

Side Effects (Estrogenic):
Dihydrotestosterone is not aromatized by the body, and is
not measurably estrogenic. An anti-estrogen is not
necessary when using this steroid, as gynecomastia and
water retention should not be concerns even among
sensitive individuals. DHT also has inherent anti*
estrogenic properties, competing with other substrates
for binding to the aromatase enzyme. Percutaneous
dihydrotestosterone may be an effective option for the
treatment of gynecomastia. Studies have reported a good
level of success when treating certain forms of this
disorder with Andractim, the drug affecting the ratio of
androgenic to estrogenic action in the breast area enough
that a notable regression of mammary tissue has been
achieved in many cases.

Side Effects (Androgenic):
Dihydrotestosterone is the strongest natural male
androgen. Higher than normal therapeutic doses are likely
to produce androgenic side effects including oily skin,
acne, and body/facial hair growth. Men with a genetic
predisposition for hair loss (androgenetic alopecia) may
notice accelerated male pattern balding. Women are
warned of the potential virilizing effects of
anabolic/androgenic steroids, especially with a strong
androgen such as dihydrotestosterone.These may include
deepening of the voice, menstrual irregularities, changes
in skin texture, facial hair growth, and clitoral
enlargement. Note that the 5-alpha reductase enzyme
does not metabolize dihydrotestosterone, so its relative
androgenicity is not affected by finasteride or dutasteride.

Side Effects (Hepatotoxicity):
Dihydrotestosterone does not have hepatotoxic effects;
liver toxicity is unlikely.

Side Effects (Cardiovascular):
Anabolic/androgenic steroids can have deleterious effects
on serum Cholesterol. This includes a tendency to reduce
HDL (good) cholesterol values and increase LDL (bad)
cholesterol values, which may shift the HDL to LDL
balance in a direction that favors greater risk of
arteriosclerosis. The relative impact of an
anabolic/androgenic steroid on serum lipids is dependant
on the dose, route of administration (oral vs. injectable)
type of steroid (aromatizable or non-aromatizable), and
level of resistance to hepatic metabolism
Anabolic/androgenic steroids may also adversely affect
blood pressure and triglycerides, reduce endothelia
relaxation, and support left ventricular hypertrophy, and
potentially increasing the risk of cardiovascular disease
and myocardial infarction. Therapeutic doses of
dihydrotestosterone used to correct insufficient androgen
production in otherwise healthy aging men are unlikely to
increase atherogenic risk. Higher doses are likely to
increase atherogenic risk, but less dramatically than
equivalent doses of synthetic oral anabolic/androgen
steroids.
To help reduce cardiovascular strain it is advised to
maintain an active cardiovascular exercise program and
minimize the intake of saturated fats, cholesterol, and
simple carbohydrates at all times during active AA
administration. Supplementing with fish oils (4 grams per
day) and a natural cholesterol/antioxidant formula such as
Lipid Stabil or a product with comparable ingredients
also recommended.

Side Effects (Testosterone Suppression): [cut off page]
All anabolic/androgenic steroids when taken in doses
sufficient to promote muscle gain are expected to
suppress endogenous testosterone production. Without
the intervention of testosterone stimulating substance
testosterone levels should return to normal within ?
months of drug secession. Note that prolonged
hypogonadotrophic hypogonadism can develop
secondary to steroid abuse, necessitating medical
intervention.

The above side effects are not inclusive. For more detaill
discussion ofpotential side effects, see the Steroid Side EffeJ
section of this book.

Administration (Men):
To treat androgen insufficiency, hydroaIcohol
transdermal dihydrotestosterone gels have been used in
doses ranging from 16 to 64mg per day (l.6-6.4mg
hormone delivered). For physique- or performance
enhancing purposes, higher doses would be necessary to
achieve strong supraphysiological levels
dihydrotestosterone. Logical effective doses begin in the
range of 50-100 mg per day, or 5-10 mg of hormone

------------------------------------------

delivered systemically. Dihydrotestosterone is of little
value for building muscle, and is most commonly applied
for cutting or pure-strength-promoting purposes.

Administration (Women):
Hydroalcoholic transdermal dihydrotestosterone gel is
not recommended for women for physique- or
performance-enhancing purposes due to its strong
androgenic nature and tendency to produce virilizing side
effects.

Availability:
Andractim is not widely available, and is rarely seen on the
black market. It is sold in several countries, but steroid
dealers and consumers just do not pay enough attention
to it for it to circulate in any volume. When found, an
Andractim product is likely to be legitimate.

[phallic1]

Some studies on the effects of DHT Gel

Results of using DHT Gel in Older Men with Partial Androgen Deficiency - note negative feedback on HTPA • PROPECIAHELP: Unresolved Finasteride Propecia Proscar side effects info & discussion forum

http://jcem.endojournals.org/cgi/content/full/87/4/1467

[curreton]

SO...how am i supposed to get this stuff in the US?! Hahaha...ugh. Just my luck. Is there anything else out there that mimics Andractim gel? I've been on test boosters for bodybuilding for a while...and I'm wondering if that might do the trick, though it's difficult to target that particular area when you take them orally! Thanks for any help!

[Maximus84]

I am about to try Andractim for 3-4 weeks very soon. Will report back with gains and experiences.

[crayrobs1]

I am now on a DHT regimen of applying it right before and after using the extender. My theory (with no research to back this guys... sorry) is that once we begin the process of cell break down, injury, then repair (with hopefully more cells produced to repair = enlargement) the cells that are produced MAY be somewhat less differentiated than when mature. This is a common process in our body with cell replication - e.g. when white blood cells form, they start fairly undifferentiated (blasts) then move on towards their mature end point (e.g. neutrophil). During the time that the cells in the penis are going through this maturation process, I am counting on them being MORE receptive to DHT to spur greater growth and replication (as occurs during puberty) before the down-regulation occurs when the cell matures. The timing may be important, so if this approach doesn't accelerate growth, then I may apply the DHT at a later time AFTER stretching and see what happens. ARGH! What I need is about 1000 guys in a study to see if this works. Also need a study to see WHEN the cells in the penis start regrowth after trauma.

[cincinnati]

Andractim - or more to the point DHT - likely does have marginally productive uses in a PE regime, especially for those that are younger (have a much higher incidence of receptors for DHT) however I'd caution users that even the topical application largely systematizes. Thus Andractim will travel throughout the body via the blood stream, causing/aggravating hair loss for the majority of men, and promoting protein synthesis in skeletal muscle, aiding visceral fat loss, and increasing one's "bad" cholesterol. A cheaper alternative to Andractim if bought through the ridiculous All Saints site would be Proviron (mesterolone). In that regard, if one desires to take Andractim, Besins Healthcare of France makes the product. You are getting ripped off in the extreme buying it from the All Saints site; unfortunately for US users, Besins no longer distributes the product in NA but it can be ordered by a physician. Andractim is widely available in France, Switzerland, and Benelux countries so perhaps a member of this site lives/travels to one of those locales frequently and can obtain a script for it. I am unsure of the exact cost though a Besins rep responded that a vial would likely cost retail less than 20 euros (~$26 USD).

[Phaseshift]

I will be getting two tubes of this stuff in the next week and half, I will keep a log on my progress. For some that have used it, do you need to apply it directly to the penis or can I apply it in my inner arms? And how many grams did you use?

I am planning to apply it after using my Bathmate. How long does it take to go through your blood stream and cycle through your system? I was thinking of maybe applying it 30 mins before my bathmate session

[shane_syndrome]

I don't think the dose is efficient , I will be injecting the stuff mid September

[crayrobs1]

I don't think the dose is efficient , I will be injecting the stuff mid September

Where did you find injectable DHT? Will you be injecting directly into the penis or simply high dose IM?