Which would you choose?

[bobberick Senior Member Find all posts View Profile Close bobberick]

L-Arginine or L-Lysine?

I've recently determined that I am trying to add too many supplements at once. I am queazy, nauseous, sweaty and lightheaded. So I'm biting the bullet, scaling back, and starting slow. I am ok to take a multi-vitamin and zinc each day. Then, I'm looking to add stuff in every now and then. Which of the two above would you add first? Any arguments for or against would be helpful in my decision. Thanks!

Bob

[blink2000 Senior Member Find all posts View Profile Close blink2000]

Add one supplement at a time. It is time consuming, but perhaps that will reveal the issue to you.

It sounds like you're already doing that.

I'm sure others will have better advice.

[GTO Retired ModeratorPEGym EditorPEGym Hero Find all posts View Profile Close GTO]

I've had issues with L-Arginine as a supplement in the past since it can be found in soooooo many foods that you eat every day. I cut back on it and started taking Lysine to balance things out. Seems to work for me.

[bobberick Senior Member Find all posts View Profile Close bobberick]

Yeah Blink... That's definitely what I'm trying to do.

[CUSP82 Administrator Admin of the Month Dec 2014PEGym Hero Find all posts View Profile Close CUSP82]

How old are you?

[bobberick Senior Member Find all posts View Profile Close bobberick]

33 years young.

[WhatAwanker Senior Member Find all posts View Profile Close WhatAwanker]

i try to keep it simple and im feeling A-ok
fishoil omega-3 2 capsules a day
longo-vital with acai berries(also contains regular vitamin pill dosage) 2 capsules a day
was taking calcium and garlic extract pills as well but stommack didnt like it so i scratch those

[cameraobscura Senior Member Find all posts View Profile Close cameraobscura]

Heads up- the zinc tears me up like crazy.

I had to throw away the bottle one night because I was so tired of the nausea... then I switched to the lozenges, and even they made me a little queazy this morning!

Maybe try laying off of the zinc a bit, I'll bet you'll feel much better. Now I see you said zinc was no problem... oh well...

[CUSP82 Administrator Admin of the Month Dec 2014PEGym Hero Find all posts View Profile Close CUSP82]

Zinc can be more of a problem than it's worth for younger guys like yourself. Multivitamins tend to give you enough zinc for a younger guy. It's when you get older and start dealing with prostate issues that extra zinc become more important.

[bobberick Senior Member Find all posts View Profile Close bobberick]

The zinc I've been taking regularly for a while with no problems. Would you suggest dropping it in lieu of one or both of the pre-mentioned supplements?

[bobberick Senior Member Find all posts View Profile Close bobberick]

I'm not a fan of bumping, but was really hoping for more input on the arg/lys choice. Anyone else? Before the weekend and I'm without a computer.

[blink2000 Senior Member Find all posts View Profile Close blink2000]

I take nitrix daily which has 1500mg of L-Arginine

LYSINE (From Wikipedia)

Lysine (abbreviated as Lys or K)[1] is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that the human body cannot synthesize it. Its codons are AAA and AAG.
Lysine is a base, as are arginine and histidine. The ε-amino group often participates in hydrogen bonding and as a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications at lysine residues include acetylation and ubiquitination. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.

Biosynthesis
As an essential amino acid, lysine is not synthesized in animals, hence it must be ingested as lysine or lysine-containing proteins. In plants and bacteria, it is synthesized from aspartic acid (aspartate):[2]

Metabolism
Lysine is metabolised in mammals to give acetyl-CoA, via an initial transamination with α-ketoglutarate. The bacterial degradation of lysine yields cadaverine by decarboxylation.
Allysine is a derivative of lysine, used in the production of elastin and collagen. It is produced by the actions of the enzyme lysyl oxidase on lysine in the extracellular matrix and is essential in the crosslink formation that stabilizes collagen and elastin.

Dietary sources
The human nutritional requirement is 1–1.5 g daily. It is the limiting amino acid (the essential amino acid found in the smallest quantity in the particular foodstuff) in all cereal grains, but is plentiful in all pulses (legumes). Consequently, meals that combine cereal grains and legumes, such as the Indian dal with rice, Middle Eastern hummus and/or ful mudammes and/or falafel with pita bread, and the Mexican beans with rice and/or tortilla have arisen to provide complete protein in diets that are, by choice or by necessity, vegetarian.
Foods containing significant amounts of lysine include:[citation needed]
Carob, Locust Bean, St.John's-Bread (26,320 ppm) in seed;
Soybean (24,290–26,560 ppm) in seed.
Asparagus Pea, Winged Bean (aka Goa Bean) (21,360–23,304 ppm) in seed.
White Lupin (19,330–21,585 ppm) in seed.
Black Caraway, Black Cumin, Fennel-Flower, Nutmeg-Flower, Roman Coriander (16,200–20,700 ppm) in seed.
Red meat (14,200–15,000 ppm)
Buffalo Gourd (10,130–33,000 ppm) in seed
Lentil (7,120–23,735 ppm) in sprout seedling.
Ben Nut, Benzolive Tree, Jacinto (Sp.), Moringa (aka Drumstick Tree, Horseradish Tree, Ben Oil Tree), West Indian Ben (5,370–25,165 ppm) in shoot.
Fat Hen (3,540–22,550 ppm) in seed.
Pea (3,170–14,995 ppm) in seed.
Common Bean (Black Bean, Dwarf Bean, Field Bean, Flageolet Bean, French Bean, Garden Bean, Green Bean, Haricot, Haricot Bean, Haricot Vert, Kidney Bean, Navy Bean, Pop Bean, Popping Bean, Snap Bean, String Bean, Wax Bean) (2,390–25,700 ppm) in sprout seedling;
Spinach (1,740–20,664 ppm).
Watercress (1,340–26,800 ppm) in herb.
Amaranth, Quinoa
Buckwheat
Eggs
Mesquite.
Good sources of lysine are foods rich in protein such as soy, as well as meat (specifically red meat, lamb, pork, and poultry), cheese (particularly Parmesan), certain fish (such as cod and sardines), and eggs.[7]

Properties
L-Lysine is a necessary building block for all protein in the body. L-Lysine plays a major role in calcium absorption; building muscle protein; recovering from surgery or sports injuries; and the body's production of hormones, enzymes, and antibodies.

Clinical significance
It has been suggested that lysine may be beneficial for those with herpes simplex infections.[9] However, more research is needed to fully substantiate this claim. For more information, refer to Herpes simplex - Lysine.
There are Lysine conjugates that show promise in the treatment of cancer, by causing cancerous cells to destroy themselves when the drug is combined with the use of phototherapy, while leaving non-cancerous cells unharmed.[10]
While chemically insignificant to lysine itself, it is worth noting that lysine is attached to dextroamphetamine to form the prodrug lisdexamfetamine (Vyvanse). In the gastrointestinal tract, the lysine molecule is cleaved from the dextroamphetamine, thereby making oral administration necessary.
According to animal studies, lysine deficiency causes immunodeficiency.[11] One cause of relative lysine deficiency is cystinuria, where there is impaired intestinal uptake of basic, or positively charged amino acids, including lysine. The accompanying urinary cysteine results from that the same deficient amino acid transporter is normally present in the kidney as well.

Source: Lysine Wikipedia

[blink2000 Senior Member Find all posts View Profile Close blink2000]

One last note, in the movie "Jurassic Park", the dinosaurs were engineered so they couldn't produce lysine so supposedly they couldn't survive outside the park.

L-Lysine is an essential amino acid, so it's one of the few our body can't produce. It does appear readily available in many types of food (see the quote above). We can get it just from eating red meat.

L-Arginine

Erectile Dysfunction
L-arginine has been used for erectile dysfunction. Like the drug sildenafil citrate (Viagra), L-arginine is thought to enhance the action of nitric oxide, which relaxes muscles surrounding blood vessels supplying the penis. As a result, blood vessels in the penis dilate, increasing blood flow, which helps maintain an erection. The difference in how they work is that Viagra blocks an enzyme called PDE5 which destroys nitric oxide and L-arginine is used to make nitric oxide.

In one study, 50 men with erectile dysfunction took either 5 grams of L-arginine per day or a placebo. After six weeks, more men in the L-arginine group had an improvement compared to those taking the placebo.
Unlike Viagra, L-arginine must be taken daily.

Wound healing
L-arginine's possible activity in wound repair may be due to its role in the formation of L-proline, an important amino acid that is essential for the synthesis of collagen.

Source: L-Arginine

We can also get L-Arginine in our diet.

I do wonder though, why is this an 'either or' question?

[Hope2GrowIt Junior Member Find all posts View Profile Close Hope2GrowIt]

Heads up- the zinc tears me up like crazy.

I had to throw away the bottle one night because I was so tired of the nausea... then I switched to the lozenges, and even they made me a little queazy this morning!

Maybe try laying off of the zinc a bit, I'll bet you'll feel much better. Now I see you said zinc was no problem... oh well...

I take a 50mg zinc tablet split in half. One half with breakfast. The other with lunch. No nausea problems any more.

[kingpole Retired ModeratorPEGym Hero Find all posts View Profile Close kingpole]

Zinc and B vitamins can give you nausea if you take them on an empty stomach. Definately do not take them with soda.