optimal testosterone

[Silver fox]

Hello, Silver Fox here. Long time reader, finally going to chime in. Have been on TRT for a long time, probably 10+ yrs or better. Started out on striant tabs 30 mg, then got to a point those didn't last as long as before. 12 hr tab lasted 8. So then my doctor switched me to the gel pump, 40 mg. I felt good, no worries always happy and nothing ever bothered me but had problems with no sex drive or getting a erection. Switched doctors and got checked last summer by new nurse practitioner. I'm 51, test results were 1198 my/dl. She cut my dosage in half. After that I had sex drive and libido good times. But also I started having the old stress and anxiety doubting myself and mood swings with people and no energy So I have a new appointment with a urologist at the end of February to finally get it under control. One problem I have is I'm always afraid the doctors aren't going to believe me.
Anyhow, I will keep update posted
Thanks for reading

[Pegasus]

Hello, Silver Fox here. Long time reader, finally going to chime in. Have been on TRT for a long time, probably 10+ yrs or better. Started out on striant tabs 30 mg, then got to a point those didn't last as long as before. 12 hr tab lasted 8. So then my doctor switched me to the gel pump, 40 mg. I felt good, no worries always happy and nothing ever bothered me but had problems with no sex drive or getting a erection. Switched doctors and got checked last summer by new nurse practitioner. I'm 51, test results were 1198 my/dl. She cut my dosage in half. After that I had sex drive and libido good times. But also I started having the old stress and anxiety doubting myself and mood swings with people and no energy So I have a new appointment with a urologist at the end of February to finally get it under control. One problem I have is I'm always afraid the doctors aren't going to believe me.
Anyhow, I will keep update posted
Thanks for reading

How very interesting . So if I read it right you were geting negative effects from a test level just outside" normal range " and in fact the sort of level some guys aim for . Shows how individual vary can affect things

[Pegasus]

https://www.pegym.com/articles/why-m...an-ever-before

[Party]

https://www.pegym.com/articles/why-m...an-ever-before

Wait a minute, so.. all mammals are showing signs of a smaller penis.
Whar Fracking scientists are measure a Polar Bear’s dick? And is it bone pressed? And does the scientist live long enough to report his findings?
Cum on, really?

[Pegasus]

I have actually seen on tv where they measure aligators .

[Pegasus]

Researchers are unlocking the mysteries of how low testosterone is related to men's overall health. Along the way, they're uncovering connections between low testosterone and other health conditions.
Diabetes, metabolic syndrome, and obesity have all been linked to testosterone deficiency. Low testosterone isn't known to cause these health problems, and replacing testosterone isn't the cure. Still, the associations between low testosterone and other medical conditions are interesting and worth a look.
Does Low Testosterone Indicate Poor Health?

In recent years, researchers have noticed general links between low testosterone and other medical conditions. One study showed that in 2,100 men over age 45, the odds of having low testosterone were:

• 2.4 times higher for obese men
• 2.1 times higher for men with diabetes
• 1.8 times higher for men with high blood pressure

Experts don't suggest that low testosterone causes these conditions. In fact, it might be the other way around. That is, men with medical problems or who are in poor general health might then develop low testosterone.
Research into the relationship between low testosterone and several other health conditions is ongoing.

Diabetes and Low Testosterone

A link between diabetes and low testosterone is well established. Men with diabetes are more likely to have low testosterone. And men with low testosterone are more likely to later develop diabetes. Testosterone helps the body's tissues take up more blood sugar in response to insulin. Men with low testosterone more often have insulin resistance: they need to produce more insulin to keep blood sugar normal.
As many as half of men with diabetes have low testosterone, when randomly tested. Scientists aren't sure whether diabetes causes low testosterone, or the other way around.
Obesity and Low Testosterone

Obesity and low testosterone are tightly linked. Obese men are more likely to have low testosterone. Men with very low testosterone are also more likely to become obese.

Fat cells metabolize testosterone to estrogen, lowering testosterone levels. Also, obesity reduces levels of sex hormone binding globulin (SHBG), a protein that carries testosterone in the blood. Less SHBG means less free testosterone.
Losing weight through exercise can increase testosterone levels.

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Metabolic Syndrome and Low Testosterone

Metabolic syndrome is the name for a condition that includes the presence of abnormal cholesterol levels, high blood pressure, waistline obesity, and high blood sugar. Metabolic syndrome increases the risk for heart attacks and strokes.
Studies show that men with low testosterone are more likely to develop metabolic syndrome. In short-term studies, testosterone replacement improved blood sugar levels and obesity in men with low testosterone. However, testosterone therapy increases the risk of heart disease, so it is not used to treat metabolic syndrome.
Testosterone and Heart Disease

Testosterone has mixed effects on the arteries. Many experts believe testosterone contributes to the higher rates of heart disease and high blood pressure that tend to affect men at younger ages. By this reasoning, high testosterone might be bad for the heart.
But testosterone deficiency is connected to insulin resistance, obesity, and diabetes. Each of these problems increases cardiovascular risk. Men with diabetes and low testosterone also have higher rates of atherosclerosis, or hardening of the arteries.
A certain amount of testosterone may be necessary for healthy arteries because it's converted into estrogen, which protects arteries from damage. As yet, no studies show that testosterone replacement protects the heart or prevents heart attacks.

Testosterone and Other Conditions

Low testosterone often exists with other medical conditions:

• Depression: In a study of almost 4,000 men older than 70, those with the lowest testosterone levels were more than twice as likely to be depressed. This link remained even after allowing for age, general health, obesity, and other variables.
• Erectile dysfunction (ED): Problems with erections and libido (sexual desire) are common symptoms of low testosterone. While most ED in older men is caused by atherosclerosis, an evaluation for low testosterone may be warranted.

Testosterone Replacement Treatment Options

The question that remains is, does low testosterone cause or worsen medical problems like diabetes? Or are people who develop diabetes, or other health problems, simply more likely to also have low testosterone?
Studies to answer these questions are under way, but it will be years before we know the results. In the meantime, remember that testosterone replacement hasn't been conclusively shown to improve any health condition other than testosterone deficiency and its symptoms. For men with low testosterone levels as measured by a blood test who also have symptoms of low testosterone, the decision to take testosterone replacement is one to make with your doctor.
Testosterone Replacement Therapy (TRT) should only be used for men with low testosterone for erectile dysfunction/low libido. It is also indicated for transgender Female>Male assignments.

[Thick_Unit]

so it has to do with diet correct the standard american diet...considering it's physically impossible to make amino acids from plants (as a human anyways)



also on SHBG I thought SHBG bind to any sex hormone? so a lower one would be way more beneficial considering the more plants you eat the more SHBG you make.. cough starvation/malnutrition this is why people who're vegan become sterile .. natures way of saying don't make any offspring because your barely making it by as it is..

mine was 15.9 but free testosterone was 2.2% despite only being 356ng.dl I get my results later today so I will know if eating the meat helped ( but i have seen quite the effect it has had on my body)

literally my Gut has disappeared it's almost completely flat(i'm at 197 pounds)

[Pegasus]

So I keep seeing info that while test is only one factor in muscle growth the effect is positive and dose dependent.
Quote
Sinha-Hikim et al. (2002) found a dose-dependent increase in the mean number of myonuclei found in skeletal muscle fibers (vastus lateralis muscle) with testosterone supplementation, as well as in the number of myonuclei per fiber (see also Eriksson et al. 2005). This increase was also associated with an increase in the number of satellite cells in the muscle tissue (but see Eriksson et al. 2005). Satellite cells are progenitor cells found external to muscle fibers that are incorporated into fibers and promote repair and growth of the muscle (Kadi and Thornell 2000; Reimann et al. 2000). However, the mechanism by which testosterone causes an increase in the number of satellite cells is unknown and could be due to testosterone (1) promoting cell division of satellite cells, (2) inhibiting apoptosis of satellite cells, or (3) causing differentiation of stem cells into satellite cells (Sinha-Hikim 2002). In any case, the functional implications for these findings are clear. More satellite cells likely result in more myonuclei per fiber, which, combined with increased protein synthesis, contribute to increases in muscle growth via an increased number and hypertrophy of muscle fibers (Kadi 2000; Kadi and Thornell 2000).