Priorly people believed that the interior of the corpora cavernosa which is filled with sinusoids (Lacunar spaces) were lined by endothelial cells which were solely responsible for separating the blood tissue barrier. Recent studies show that these cells are responsible for highly sophisticated functions such as: secretory, synthetic, metabolic, and immunologic functions as well as responsible for growth, blood flow, development, and tissue formation.
What does this mean?
These linings create formation of new blood vessels, and generate smooth muscle in response to stress, mechanical force, and other interesting exogenous factors.
So this leads to two causes of penile growth:
Fibroblast - cells that synthesize extracellular matrix and collagen.
this is stimulated by tissue damage which induces mitosis of fibroblasts
and Vascular endothelial growth factors (heres where it gets interesting...)
This is stimulated by an enzyme called tyrosine kinase which is aphosphate group that uses a process called Phosphorylation to signal cells and regulate cell activity such as cell division.
these processes are stimulated and can cause smooth muscle tone under the following scenarios :
Hypoxia -Deficiency in the amount of oxygen reaching the tissues.
Shear stress
Ischemia - A decrease in the blood supply to a bodily organ, tissue, or part caused by constriction or obstruction of the blood vessels
How to expedite the growth:
The factors that stimulate Nitric oxide reduce cell multiplication and proliferation which makes PE limit itself to increasing smooth muscle tone and makes growth more difficult....
by taking Nitric Oxide inhibitors and doing pe at the same time you simulate the environmental influences that expedite cell growth and multiplication
On top of inhibiting the NO, you take supplements that are responsible for transferring phosphates and proteins to deliver nutrients to newly growing cells by speeding up the tyrosine kinase transfer process. This can be done by manipulating phosphorylation that uses tyrosine and threonine to expedite cell multiplication and growth through the endothelium system.
What does this mean?
These linings create formation of new blood vessels, and generate smooth muscle in response to stress, mechanical force, and other interesting exogenous factors.
So this leads to two causes of penile growth:
Fibroblast - cells that synthesize extracellular matrix and collagen.
this is stimulated by tissue damage which induces mitosis of fibroblasts
and Vascular endothelial growth factors (heres where it gets interesting...)
This is stimulated by an enzyme called tyrosine kinase which is aphosphate group that uses a process called Phosphorylation to signal cells and regulate cell activity such as cell division.
these processes are stimulated and can cause smooth muscle tone under the following scenarios :
Hypoxia -Deficiency in the amount of oxygen reaching the tissues.
Shear stress
Ischemia - A decrease in the blood supply to a bodily organ, tissue, or part caused by constriction or obstruction of the blood vessels
- These three factors result in an increased intracellular calcium concentration and, in turn, increases vascular smooth muscle cell tone
- (these are all consistent with the PE exercises and how they create growth)
How to expedite the growth:
- The cause of smooth muscle growth and proliferation is from certain dysfunctions like atherosclerosis that block blood vessels and reduce concentrations of bioactive Nitric Oxide. This is why people with sickle cell anemia can get the condition of megaphallus. When your natural NO levels are suppressed enough, this allows unopposed actions of endothelin-1 to promote vasoconstriction and smooth muscle proliferation.
- this is why you have people with sickle cell anemia having huge penises.
The factors that stimulate Nitric oxide reduce cell multiplication and proliferation which makes PE limit itself to increasing smooth muscle tone and makes growth more difficult....
by taking Nitric Oxide inhibitors and doing pe at the same time you simulate the environmental influences that expedite cell growth and multiplication
On top of inhibiting the NO, you take supplements that are responsible for transferring phosphates and proteins to deliver nutrients to newly growing cells by speeding up the tyrosine kinase transfer process. This can be done by manipulating phosphorylation that uses tyrosine and threonine to expedite cell multiplication and growth through the endothelium system.
Comment